NAD+ Injection Dosage Chart 2026 — IV & SubQ Dose Reference

Medical Disclaimer

This website is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, changing, or stopping any medication or supplement. Dosage information reflects published FDA-approved labeling or publicly available clinical trial data — individual treatment decisions must be made by a licensed physician.

About Nicotinamide Adenine Dinucleotide (NAD+)

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme used in compounded injectable and IV therapies for energy, cellular health, and anti-aging purposes. It is not FDA-approved as a drug. This page provides reference information on doses used in wellness and functional medicine contexts.

Indication

Wellness/functional medicine use. NOT FDA-approved. Not a GLP-1 medication. Consult a licensed provider.

Research / Trial Dosing Reference

Dosing data from published clinical trials. Not an approved prescription protocol.

Week / Phase	Dose	At 2.5 mg/mL	At 5 mg/mL	Notes
Subcutaneous low dose	50 mg	10 units (50 mg/mL)	5 units (100 mg/mL)	Conservative subcutaneous starting dose. Often used daily.
Subcutaneous standard dose	100 mg	20 units (50 mg/mL)	10 units (100 mg/mL)	Common subcutaneous maintenance dose.
IV low dose	250 mg	250 units (100 mg/mL)	—	Lower IV infusion dose. Must be run slowly (>1–2 hours) to prevent flushing and chest tightness.
IV standard dose	500 mg	500 units (100 mg/mL)	—	Standard IV infusion dose. Run over 3–4 hours minimum.
IV high dose	1000 mg	1000 units (100 mg/mL)	—	High IV dose used in some anti-aging protocols. Run over 6–8 hours.

Units shown assume a standard U-100 insulin syringe (100 units = 1 mL). Always confirm your vial concentration with your pharmacy.

Dose Calculator

Enter your prescribed dose and vial concentration to calculate how many units to draw.

mg ↔ Units Dose Calculator

Convert between milligrams and insulin-syringe units for compounded GLP-1 medications. Uses a standard U-100 syringe (100 units = 1 mL).

Medication

Vial Concentration (mg/mL)

Dose (mg)

Units (U-100 syringe)100 units

Volume1.000 mL

2.5 mg at 2.5 mg/mL → 1.000 mL → 100 units on a U-100 (100-unit / 1 mL) insulin syringe

Always verify calculations with your prescribing provider or pharmacist before administering any medication. This calculator is for reference only.

Injection Sites

Subcutaneous (abdomen)

SubQ injection into abdominal fatty tissue for at-home protocols.

Use a 29–31 gauge needle
Rotate sites daily
Burning sensation is common — inject slowly

IV (peripheral vein)

Intravenous infusion typically administered in a clinic.

Must be administered by trained personnel
Run slowly to minimize flushing, chest tightness, and nausea
Side effects are rate-dependent — slow the drip if symptoms occur

Storage Instructions

Refrigerate compounded NAD+ solutions
Protect from light — use amber vials
Check expiration with compounding pharmacy
Do not freeze IV solutions

Common Side Effects

Contact your healthcare provider if side effects are severe or persistent.

IV: Flushing, chest tightness, nausea, headache (rate-dependent — slow the infusion)
SubQ: Injection site burning, itching
Fatigue or energy surge (paradoxical response possible initially)

Frequently Asked Questions

What is NAD+ used for?

NAD+ is promoted in wellness contexts for cellular energy production, anti-aging, cognitive function, addiction recovery support, and metabolic health. Clinical evidence for these uses varies from preliminary to very limited.

How much NAD+ should I take?

There is no FDA-established dose. Wellness practitioners typically start subcutaneous injections at 50–100 mg/day and IV infusions at 250–500 mg per session. Individual response varies considerably. Always work with a licensed provider.

Can I do NAD+ injections at home?

Some providers prescribe compounded NAD+ for subcutaneous at-home use. IV infusions require clinical administration. Always obtain NAD+ from a licensed compounding pharmacy and follow your provider's instructions.