Medical Disclaimer
This website is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, changing, or stopping any medication or supplement. Dosage information reflects published FDA-approved labeling or publicly available clinical trial data — individual treatment decisions must be made by a licensed physician.
About Growth Hormone Releasing Peptides (Sermorelin, Ipamorelin, CJC-1295)
Growth hormone secretagogue peptides (sermorelin, ipamorelin, CJC-1295) stimulate the pituitary to produce more growth hormone. Sermorelin is the only FDA-approved peptide in this class; ipamorelin and CJC-1295 are research compounds. Dosing is highly variable and provider-dependent.
Indication
Growth hormone deficiency (sermorelin, FDA-approved). Ipamorelin and CJC-1295 are not FDA-approved. Research/wellness use only.
Research / Trial Dosing Reference
Dosing data from published clinical trials. Not an approved prescription protocol.
| Week / Phase | Dose | At 2.5 mg/mL | At 5 mg/mL | Notes |
|---|---|---|---|---|
| Sermorelin starting | 200 mcg | 10 units (2 mg/mL) | 4 units (5 mg/mL) | Common starting dose for sermorelin therapy. Administered at bedtime. |
| Sermorelin maintenance | 300 mcg | 15 units (2 mg/mL) | 6 units (5 mg/mL) | Common maintenance dose. |
| Ipamorelin standard | 200 mcg | 10 units (2 mg/mL) | 4 units (5 mg/mL) | Common research dose for ipamorelin. Not FDA-approved. |
| CJC-1295 (with DAC) standard | 1–2 mg | 75 units (2 mg/mL) | 30 units (5 mg/mL) | CJC-1295 with DAC has a longer half-life — often dosed 1–2x per week. Not FDA-approved. |
Units shown assume a standard U-100 insulin syringe (100 units = 1 mL). Always confirm your vial concentration with your pharmacy.
Dose Calculator
Enter your prescribed dose and vial concentration to calculate how many units to draw.
mg ↔ Units Dose Calculator
Convert between milligrams and insulin-syringe units for compounded GLP-1 medications. Uses a standard U-100 syringe (100 units = 1 mL).
2.5 mg at 2.5 mg/mL → 1.000 mL → 100 units on a U-100 (100-unit / 1 mL) insulin syringe
Always verify calculations with your prescribing provider or pharmacist before administering any medication. This calculator is for reference only.
Injection Sites
Subcutaneous (abdomen or thigh)
SubQ injection before bedtime into abdominal or thigh fat.
- Bedtime injection aligns with natural GH secretion pattern
- Rotate sites to prevent local reactions
- Use 29–31 gauge insulin syringe
- Fast for 2–3 hours before injection (food blunts GH response)
Storage Instructions
- Lyophilized (freeze-dried) peptide: store frozen or refrigerated
- After reconstitution with bacteriostatic water: refrigerate, use within 30 days
- Protect from light
- Do not shake — gently swirl to mix
Common Side Effects
Contact your healthcare provider if side effects are severe or persistent.
- Water retention (bloating)
- Joint stiffness
- Numbness or tingling (carpal tunnel-like symptoms)
- Injection site redness
- Increased hunger
- Vivid dreams (related to GH increase)
Frequently Asked Questions
What is the difference between sermorelin and ipamorelin?
Is CJC-1295 the same as sermorelin?
Why take HGH peptides before bed?
Primary Source
FDA / Clinical Source
Dosing information sourced from: https://www.accessdata.fda.gov/drugsatfda_docs/label/1996/020408lbl.pdf
Related Guides
Retatrutide Dosage Chart
(Investigational — LY3437943)
Retatrutide dosage overview — clinical trial dosing data
Cagrilintide Dosage Chart
CagriSema (combination with semaglutide — investigational)
Cagrilintide dosage — amylin analogue overview
BPC-157 Dosage Chart
Research peptide — not FDA-approved
BPC-157 dosage reference — research peptide guide